Skin barrier defects caused by filaggrin gene mutations allow allergens to penetrate the epidermis and interact with antigen-presenting cells, leading to the development of atopic disorders, including asthma. Studies have shown that between 25%-50% of patients with atopic dermatitis have filaggrin mutations. These mutations are also linked to atopic dermatitis-associated asthma and allergic rhinitis. In the case of atopic dermatitis, restoration of the skin barrier function seems to be a good prophylactic strategy.
Source: Allergology International
Click here for more research on possible causes of eczema
For LINKS to freefrom skin care products click here.
Top of page |
