Combining probiotics may improve adult eczema

A study to determine whether combining probiotics can have a beneficial effect on atopic dermatitis (AD) in adults has found that a specific mixture of Lactobacillus salivarius (LS01) and Bifidobacterium breve (BR03) may modify the progression of AD, and be used as an additional therapy in the treatment of AD in adults.

Researchers in the Allergy and Clinical Immunology Unit at the L. Sacco Hospital, Milan, Italy had 48 AD patients in the study. The 48 were randomly treated for 12 weeks with either a combination of LS01 and BR03 or a maltodextrin placebo. Changes in their symptoms were measured using the SCORAD index and DLQ index improvement. Analysis on the gut permeability barrier, immunologic parameters and changes in fecal microbiota and recovery of probiotics were performed at the beginning and end of the therapy, and two months later.

The patients who received the probiotic combination showed a significant improvement, and none of the beneficial changes observed in this group were observed in the placebo group.

Source: Journal of Clinical Gastroenterology

October 2012

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