Partially hydrolysed cow’s milk formula has been found to have beneficial effects on infants with mild atopic dermatitis

Researchers from the Department of Paediatrics, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, carried out a study between 2006-2008 on 113 infants of less than six months old, to determine whether partially hydrolysed cow’s milk formula (phCMF) is beneficial for the treatment of atopic dermatitis (AD). Previous studies have demonstrated the allergy-preventing effect of phCMF in infants with a high-risk of AD. The researchers focused on infants with mild to moderate AD in this study.

The infants were randomised to receive either conventional or partially hydrolysed cow’s milk formula. Assessments were made at the beginning, at weeks 4, 8 and 12. AD severity in infants was measured using the Japanese Dermatological Association Scoring System (JDASS) and SCORAD.

By the end of the study 27 infants had dropped off the study, leaving 86. AD severity scores were significantly lower in the group that had been given the phCMF compared to those on the conventional CMF.

The study therefore suggests that phCMF can be used to treat infants with mild to moderate AD during the first 6 months of their life without affecting their nutritional status.

Source: Pediatric Allergy and Immunology

November 2011


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